Conventional Raman and surface-enhanced Raman spectroscopy for human skin components analysis

In the current work the spectral characteristics of amino acids such as arginine, lysine, glycine, tyrosine, cystine are investigated. The comparative analysis results of arginine, lysine, glycine and tyrosine characteristics were obtained using Raman scattering in the visible region (532 nm central wavelength) and Raman scattering in the near infrared region (785 nm central wavelength). In addition, the possibility of using surface-enhanced Raman spectroscopy in the near infrared region (785 nm central wavelength) was analysed using cystine as an example. The revealed spectral features of the studied amino acids can be used as basis for studying the topology of proteins and peptides in human skin during the presence of pathological processes in the body.