An Electrospun Nanofibrous Membrane Based Electrochemical Glucose Sensor

This letter presents a conductive polymer based electrospun-nanofibrous-membrane (ENFM) for an enzymatic electrochemical glucose sensor. The ENFM-based sensor electrode shows a wide detection range from 0 to 25 mM concentration with a shorter response time of less than 4 s and the sensitivity of 5.11 μA/mM cm
²
with a limit of detection 2.3 μM in a glucose buffer solution. The sensing electrode shows a negligible change in a current response for upto 50 days. The sensing activity of an electrode remained constant indicating a good long-term stability for the glucose sensor due to the direct immobilization of glucose oxidase (GO
_x
) enzyme onto the surface of nanofibers. The electrochemical analysis results demonstrated that the ENFM-based glucose sensor provides reliable results in terms of enhanced sensitivity, good stability, durability, and quick response time for a glucose detection.