Simulation of thrombin generation during plasmatic coagulation and primary hemostasis

Describes a simulation of the platelet agglutination in a damaged vein. This agglutination, called plasmatic coagulation, appears in the human body and its malfunction involves dramatic diseases like thrombosis or hemophilia. We designed an in-machina experimentation that is very difficult to do in-vitro. The first aim of this simulation is to verify one of the biological models of plasmatic coagulation and primary hemostasis. The second aim is to test different ways to regulate the thrombin production. Then, we simulate a haemophilia-like disease and one of its possible treatments.