Chattering-free Higher Order Sliding Mode and Unscented Kalman Filter for Blood Glucose Level Control

A new hybrid scheme is proposed for the blood glucose (BG) regulatory system in type-l diabetes mellitus (T1DM) patients. Some of hybrid glucose-insulin controllers have combined the artificial intelligence such as fuzzy logic and metaheuristic algorithm with well-known Palumbo model. However, most of those approaches have focused on the glucose reference tracking, and the glucose sensor errors as well as various unmeasurable disturbances have not been well studied. In this paper, a hybrid method based on higher order sliding mode (HoSM) and unscented Kalman filter (UKF) has been presented. The high performance of the proposed hybrid scheme for desired BG level tracking and chattering reduction in presence of daily glucose level disturbances has been verified.