Capacitive Detection of Insulin Antibody enhanced by AC Electrothermal mixing

Capacitive immunosensors present a useful tool for non-invasive and label-free biosensing. Readily integrable with microfluidic platforms, interdigitated electrode (IDE) arrays can be specifically functionalized to detect antibody/antigen surface binding events. Here, AC electrokinetics are used to enhance target binding to overcome long incubation times and diffusion limited miniaturization. This represents the first application of ACET enhancement for human hormone detection to be used in modeling diabetes.