Stress Effects in the Brain During Transcranial Magnetic Stimulation

We used a three-dimensional magnetic resonance image to model the Lorentz force in scalp, skull, cerebrospinal fluid, gray matter, and white matter of the human brain during transcranial magnetic stimulation (TMS). The simulations show that during TMS procedures, measurable intracranial forces develop within different tissue layers of the brain. This force strongly depends on the strength of the magnetic field generated by the TMS coil. The effect of this force will cause stress in the brain tissues and creates around 5%-10% deformation in both gray and white matter.