Study of In Vitro Diagnostic Preconcentration Technique via Surface Acoustic Wave Modified with the 54 MHz Communication Chip

Particle separation and specimen preconcentration techniques are ones of the essential but time-consuming steps in the beginning of many biomedical sensing experiments or biosensor design. Hence, the study demonstrates a simple microfluidic system combined with surface acoustic wave (SAW) device, hoping to help researchers could spend less time on this routine process. A detachable and reusable acrylic microchannel is placed on the customized SAW chip which releases a 54 MHz SAW wave to separate 10 μm particles from the others (1 μm & 6 μm) under the cut-off input power 23.4 dBm verified in the study and about 90% separation efficiency in average.