Design of a Microbiota Sampling Capsule using 3D-Printed Bistable Mechanism

Microbiota analysis is a fundamental element for a better understanding of microbiota role, its relationship with the human body and its impact on different pathologies. There is today no non-invasive tool for easy collection of the microbiota in the small intestine. In this paper, we describe the development of such a device that opens the way to new diagnostic techniques. The device is based on a capsule designed as a passive system to maximize the safety during its use. Originality of the design relies in the use of a bistable mechanism obtained using additive manufacturing in order to provide a compact design with integration of opening, sampling and closing functions within the capsule. Design, implementation and initial lab evaluation of sampling are presented.