Implementation of Mealy Machine with Molecular Reactions

Chemical reaction networks(CRNs) have been used as a formal language for constructing and analysing molecular systems. Theoretical analysis and experiments have demonstrated that CRNs could be physically implemented with DNA strand displacement reactions. This paper proposes a method of synthesizing Mealy machine with molecular reactions, which focuses on deriving CRN from state diagram of any Mealy machine. All components of the proposed design could be experimentally implemented by DNA reactions. Therefore, the proposed CRN-based Mealy machine has potential applications in \(vitro\) and in \(vivo\) biotechnology.