Cell-laden micropillars detect gaseous odorants on a liquid-air interface

We propose a gaseous odorant detection system by combination of a collagen pedestal and micro collagen pillars containing cells expressing olfactory receptor. The collagen pedestal allowed to bring cells close air-liquid surface without getting dry damage. As a result, gaseous odorants detection was achieved by shortening diffusion length. Moreover, 3D structure of pillars enhanced reaction efficiency because of large surface. Therefore, we believe that our odorant detection system will be useful gaseous odorant sensors.