Towards high-resolution brain-chip interface and automated analysis of multichannel neuronal signals

To understand brain functions and diagnose brain disorders, scientists have developed various probing tools and techniques. This development has been facilitated by the rapid growth of micro- and nano-technology over the last two decades and allowed the scientists to record neuronal signals at multiple scales and simultaneously from hundreds of channels. However, this huge amount of data poses a big challenge and requires proper interpretation before any meaning can be derived. As a response, various automated and intelligent methods and tools have been proposed for the mining of such data. Here we overview some of the high-resolution neuronal probes available at present, the neuronal signals recorded through them, and a few possible automated methods to analyze the acquired signals. Towards the end we indicate few research challenges and outlook.