Implementation of a conduction system in a model of ventricular myocardium

We implemented a method for interactive creation and manipulation of a conduction system in our computer model of the ventricular myocardium. The conduction system was defined interactively in terms of nodes and a connectivity matrix with a computer program utilizing the OpenGL capabilities of the SGI Visual PC. To validate the conduction system, simulations were run where the activation propagated from the His bundle to Purkinje myocardial junction (PMJ) sites and through the ventricular myocardium. The simulated activation sequence agreed with isochrones obtained from an isolated human heart. The calculated body surface potential maps during the initial QRS complex correlated well with our clinical recordings on normal subjects.