A 1600 by 1200, 300 mW, 40 fps multi-spectral imager for near-infrared fluorescence image-guided surgery

We have designed, fabricated, and tested a multi-spectral imager for near-infrared fluorescence image-guided surgery capable of simultaneously imaging both color and near-infrared fluorescence information with high sensitivity at 40 frames per second. The imaging sensor is composed of 1600 by 1200 imaging elements covered by pixelated spectral interference filters. The imaging sensor was successfully used in a preclinical study to assess and compare altered dynamic arterial perfusion in a murine model.