Integrated Inverse Planning Strategy Considering Total Number of Segments and Total Number of Monitor Units

Two-step inverse planning optimization model and the corresponding algorithm can solve the optimization problem from clinical needs to radiation intensity in intensity modulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT). However, from the overall inverse planning process, multi-step optimization strategy is a form of compromise for the optimization results and those complex requirements. Therefore, this paper proposed an integrated inverse planning strategy considering total number of segments and total number of monitor units. Experimental results showed that the integrated strategy with deterministic calculation algorithm obtained good results, but it comes with a price of calculation time in simultaneous. In addition, to reduce the amount of calculation and combining the beam number and beam direction into integration are the furthermore problems to be solved in the future researches.