Therapeutic effects of an anti-gravity locomotor training (AlterG) on postural balance and cerebellum structure in children with Cerebral Palsy | IEEE Conference Publication | IEEE Xplore

Therapeutic effects of an anti-gravity locomotor training (AlterG) on postural balance and cerebellum structure in children with Cerebral Palsy


Abstract:

We evaluated the therapeutic effects of anti-gravity locomotor treadmill (AlterG) training on postural stability in children with Cerebral Palsy (CP) and spasticity, part...Show More

Abstract:

We evaluated the therapeutic effects of anti-gravity locomotor treadmill (AlterG) training on postural stability in children with Cerebral Palsy (CP) and spasticity, particularly in the lower extremity. AlterG can facilitate walking by reducing the weight of CP children by up to 80%; it can also help subjects maintain an appropriate posture during the locomotor AlterG training. Thus, we hypothesized that AlterG training, for a sufficient period of time, has a potential to produce cerebellum neuroplasticity, and consequently result in an effective permanent postural stability. AlterG training was given for 45 minutes, three times a week for two months. Postural balance was evaluated using posturography. The parameters of the Romberg based posturography were extracted to quantify the Center of Balance (CoP). The neuroplasticity of Cerebellum was evaluated using a Diffusion Tensor Imaging (DTI). The evaluations were done pre- and post-training. The Fractional Anisotropy (FA) feature was used for quantifying structural changes in the cerebellum. The results showed that AlterG training resulted in an increase in average FA value of the cerebellum white matter following the training. The results of the posturography evaluations showed a consistent improvement in postural stability. These results were consistent in all subjects. Our findings indicated that the improvement in the posture was accompanied with the enhancement of the cerebellum white matter structure. The clinical implication is that AlterG training can be considered a therapeutic tool for an effective and permanent improvement of postural stability in CP children.
Date of Conference: 17-20 July 2017
Date Added to IEEE Xplore: 14 August 2017
ISBN Information:
Electronic ISSN: 1945-7901
PubMed ID: 28813801
Conference Location: London, UK

I. Introduction

Cerebral Palsy (CP) is the most prevalent motor disability of children with neurological disorders. Its prevalence is reported in the range of 1.5 to 2.5 per 1000 live births [1]. CP children usually suffer from different impairments including gait, speech, cognitive, and postural impairments [2]. Movement impairments and postural deficits are the most important symptoms of CP [3], which can cause serious dependence and can reduce the patients' quality of life [4]. Hence, CP not only has a significantly negative impact on these patients and their families, but is also very costly for the society.

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References

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