Study of the drug fiber for wound healing by direct-writing near field electrospinning with subdivision control

In this research, the mixed solution of polycaprolactone (PCL) and natural anti-inflammatory drugs (F101) in the direct writing system of near-field electrospinning (DWs-NFES) was used the uniform experimental design and controllable injection flow rate process to produce stable fibrous support structure. Finally, the mesh structure (60 × 60 mm²) of 0.89 μm drug fibers diameter was deposited. The result was confirmed the mesh structure to upgrade the fibers density in unit area. Therefore, the drug fibers of DWs-NFES were higher the gel and injured group about 3.67 times in the wound healing experiment.