Pathological brain detection based on online sequential extreme learning machine

Magnetic resonance imaging (MRI) is a kind of imaging modality, which offers clearer images of soft tissues than computed tomography (CT). It is especially suitable for brain disease detection. It is beneficial to detect diseases automatically and accurately. We proposed a pathological brain detection method based on brain MR images and online sequential extreme learning machine. First, seven wavelet entropies (WE) were extracted from each brain MR image to form the feature vector. Then, an online sequential extreme learning machine (OS-ELM) was trained to differentiate pathological brains from the healthy controls. The experiment results over 132 brain MRIs showed that the proposed approach achieved a sensitivity of 93.51%, a specificity of 92.22%, and an overall accuracy of 93.33%, which suggested that our method is effective.