Wide-field high-resolution fiber bundle based endomicroscope for cervical epithelium cells imaging

Endomicroscope is commonly used in epithelium diagnosis. We have designed a low-cost wide-field high-resolution fiber bundle based endomicroscope with off-the-shelf optical components and a commercial CMOS camera. We compensated the low sensitivity of the CMOS sensor in the camera with a suitable magnification of the optical system and image processing algorithm which is running on an embedded system. In this paper, the prototype of the designed endomicroscope can resolve a spatial resolution of 70 microns and capable of fluorescence imaging.