Machine learning-based clinical decision support system for early diagnosis from real-time physiological data

This research aims to design a self-organizing decision support system for early diagnosis of key physiological events. The proposed system consists of pre-processing, clustering and diagnostic system, based on self-organizing fuzzy logic modeling. The clustering technique was employed with empirical pattern analysis, particularly when the information available is incomplete or the data model is affected by vagueness, which is mostly the case with medical/clinical data. Clustering module can be viewed as unsupervised learning from a given dataset. This module partitions the patient vital signs to identify the key relationships, patterns and clusters among the medical data. Secondly, it uses self-organizing fuzzy logic modeling for early symptom and event detection. Based on the clustering outcome, when detecting abnormal signs, a high level of agreement was observed between system interpretation and human expert diagnosis of the physiological events and signs.