Assessment of vascular health with PPG signals from two fingertips

This study aimed at validating photoplethysmography for assessing bilateral blood pressure differences through analyzing digital volume pulse (DVP) and investigating its correlations with risk of arteriosclerosis. Bland-Altman analysis demonstrated satisfactory IDVPD reproducibility (r=0.781, p=0.023) Linear regression analysis demonstrated significant correlation between IDVPD and ECG-PWV (r=0.692, p<;0.001). Compared with ECG-PWV that demonstrated significant correlations only with age and pulse pressure, IDVPD exhibited highly significant correlations with age, HbAlc level, pulse pressure, TC/HDL ratio, CT, HDL, and systolic blood pressure (all p<;0.001). This study not only demonstrated successful application of a novel non-invasive waveform contour index, IDVPD, in differentiating young from aged subjects and patients with good from those with poor diabetic control, but also validated its use in identifying arteriosclerosis risks. The results, therefore, suggest possibility of its domestic application as a convenient non-invasive tool for arteriosclerosis risk screening.