Comparative study of electrode configurations in different brain tumor geometry for effective Electrochemotherapy

Electrochemotherapy is an effective emerging technique for cancer treatment. Electric pulses are applied to ensure proper penetration of the drugs in the tumor cell. Electrochemotherapy has a wide area of application in cancer diagnosis. Effective Electrochemotherapy involves proper selection of electrode type and configurations. In this paper, a 2D model of a brain tumor is simulated and a comparison of parallel plate electrode and different needle electrode configuration is given. Electric field analysis is performed using Finite Element Method using COMSOL Multiphysics software. The average electric field inside the tumor and the maximum electric field outside the tumor are taken as the control parameter to determine the best electrode configuration for different tumor geometry having same area.