Embryo lab chip taking advantage of microfluidics and cell co-culturing

This research serves as an in vitro platform for fertilization and embryonic development. Thin polydimethylsiloxane (PDMS) membrane was etched to create an array of through-holes, and sandwiched between two PDMS channels to form an upper chamber and lower chamber. This device integrates the concentration gradient design and perfusion system for proposed embryo coculture with stromal cells.