Target Controlled anesthetic drug infusion

Anesthetic drugs must be administered at an appropriate rate to prevent adverse reactions during ambulatory surgery and after discharge from the hospital. Target Controlled Infusion (TCI), choose the target concentration and infusion pump deliver the dose to patient. TCI helps to avoid underdose or overdose. The anesthetic drug Propofol (Diprivan) slows the motion of patient's brain and nervous system. Target controlled infusion (TCI) of propofol permit anesthetists to target constant blood concentrations and react punctually to signs of inappropriate anesthetic depth. Target Controlled Infusion (TCI) induces and preserves a drug concentration by using an internal three compartmental pharmacokinetic model. In this paper, the drug concentration which is deliver to patient is controlled by the controller, implemented on embedded system. The results shows that better accuracy is achieve with TCI as compared to manual infusion.