Low-voltage fully differential CMOS neural amplifier based on CFOA

In this paper, a low voltage fully differential neural amplifier based on current feedback operational amplifier (CFOA) is introduced. The gains of LFP and spikes signals can be tuned using the amplifiers capacitors. The designed amplifier provides a maximum output gain up to 50 dB, a total power consumption of 4.218 nW, and an input referred noise of 3.38 μV/Hz^1/2 and 5.96 μV/Hz^1/2 for LFP signals and spikes signals, respectively. Moreover, the lower cutoff frequencies of the amplifier can be tuned using the pseudo-resistor. The neural amplifier has been simulated using LTspice with a CMOS technology of 90nm provided from MOSIS and power supply voltage of ±0.6V. The simulation results is demonstrated and discussed. Also, a performance comparison between the proposed amplifier and other neural amplifiers is presented.