Steady-state visual evoked potential based classification system for detecting migraine seizures

The recurrent migraine attacks between interictal phenomenon is triggered by the migraineurs' brain lacking for habituation, due to the stimulations from the outside world that increase the excitability of brain activity, which have been considered as the possible reasons for migraine seizure. The variation of habituation level within the migraine cycle is proposed to be a critical symptom to describe the physiological states of migraine headache. This study proposed Steady-State Visual Evoked Potentials (SSVEP) examination to utilize habituation for classifying the different physiologic states of migraine cycle, and implement a classification system to determine different migraine states. The developed system may be extended to detect migraine seizure, and provide an opportunity to a clinically individual-based headache monitoring program, aiming for early migraine detection.