Influence of probe optical arrangement on biological zero in laser-Doppler perfusion measurements

Laser-Doppler method is frequently used in clinical experiments for perfusion measurement. Level of biological zero measured usually during occlusion test can be significant in evaluation of microvascular flow. In the presented study the influence of optical arrangement of laser-Doppler probe on biological zero level is discussed. Biological zero growths with the distance between emitting and receiving fibers in laser-Doppler probe and the change can be significant for probes with fibers of diameter of 200 /spl mu/m if distances are longer than 0.5 mm.