A Linear Approach to Multi-Panel Sensing in Personalized Therapy for Cancer Treatment

In this paper, a new approach for evaluating the performance of a multi-panel biosensor using linear algebra is presented. With a system-level mathematical analysis based on graphs and linear algebra, we formulate a new approach for contributions decoupling in a multi-panel biochip for simultaneous detection of anti-cancer drugs, avoiding redundancy and interaction between enzymes. Experimental results have been used to validate the model.