Enhancement of nanoelectronic sensor performance with microfluidic device

In this paper, we suggest a simple and inexpensive method for the enhancement of binding performance with low pressure drop using density difference between core fluid and sheath fluid. Simulations and parametric studies of the method have been performed using computational fluid dynamics (CFD) simulation program and the results were validated by fluorescence experiments using fluorescent polystyrene beads and streptavidin labeled with fluorescent dye.