Brain-driven micro-biomanipulation with sensing feedback

This paper presents our development of an integrated brain-driven micro-biomanipulation system that can perform mind-controlled biomanipulation at micro scale. The system incorporates a non-invasive electroencephalogram (EEG) device with a high-precision automated micromanipulator through high speed network. The human manipulation mind measured by the EEG device can effectively drive the micro-manipulator to perform the 2-D manipulation on bio-samples. During the manipulation, the trace of human manipulation mind is monitored by a custom-built high-precision position sensing detector (PSD) interface unit. Extensive experimental results demonstrate the high performance of the developed network-enabled and brain-driven micro-biomanipulation system. The research work can be further used to investigate manipulation behavior and neurobiofeedback mechanism of human brain for facilitating development of high-efficiency micro-biomanipulation strategy of engineering approaches in micro/nano level.