Study the effects of using CW and pulsed diode lasers on burns healing

This paper focused on studying the effect of diode laser on the burn healing. The study is based on using 32 mature, male albino mice divided into four groups, all groups were burned using an electrical soldering unit on the back of each mouse for five seconds to create a 3
^rd
degree burn of 1 cm in length. Two groups were treated with diode laser. The first group (S1) is treated with 785nm, 3.5mW CW diode laser for 3 minutes to get energy density = 3J/cm
²
. The second group (S2) is illuminated by using CW diode laser of 637nm, 2mW for 5 minutes with the same energy density, while the pulsed group (group S3) is treated by pulsed diode laser (637nm) of pulse repetition frequency (p.r.f) 1 KHz and duty cycles, 50%. One group of these animals was not irradiated by laser energy. It is used as a control group. The animals were irradiated three times per week. The first laser irradiation was given immediately after burn creation followed by the two other exposures at the next 2
^nd
and 3
^rd
day after burning. The histological assessment was started at day 4 after the burn and carried on for 25 days; once per week. The results showed that for a CW laser groups; the re-epithelialization appear one week earlier in laser group S2 (CW-637nm wavelength, 2mW) at day 18, while in the control group appear only at day 25 after burn. The hair follicles in this group seem to appear more quickly than the control group. The pulsed laser showed also better results comparing to the result of CW diode laser.