A smart 16-channel front-end system for extracelluar neural recording

An implantable 16-channel neural recording front-end system is presented for acute neural recording. This system consists of implantable silicon-based microelectrode arrays, neural-signal amplifiers and a microprocessor. The neural-signal amplifiers, which have been fabricated by a 0.35-μm CMOS process, have a mid-band gain of 66.5 dB, a high cut-off frequency at 9.6 kHz. Each recording channel has a tunable low cut-off frequency independently which is controlled by a microprocessor to fit different kinds of neural signals. The system has been tested and verified in-vitro experiment.