The MPI parallelization of the diffusion-drift algorithm for quantitative analysis of breast tumor electric signals

Experimental measurements on MCF-7 cells, a standard breast cancer cell line, have demonstrated that the membrane potential varies with the different stages of cell division [1]. The membrane potential was found to depolarize, that is become more positive, at the beginning of the Gap 1 (G1) stage and hyperpolarize at the Gap 1/Synthesis (G1/S) transition. The extracellular electrical signals, electric current densities and biopotentials, generated due to these depolarizations and hyperpolarizations were calculated due to a single cell in [1].