Effects of Hydroxyapatite Nanoparticles on Apoptosis of Prostate Cancer

The incidence rate of prostate cancer has increased rapidly in China, and the disease will recur in about one third of patients and there is no cure for metastatic prostate cancer. The aim of this study was to investigate the effects of hydroxyapatite nanoparticles on prostate cancer cells. Our results showed that hydroxyapatite nanoparticles significantly reduced cell proliferation, invasion and induced apoptosis in RM-1 cells. This study suggests that hydroxyapatite nanoparticles may be a potential therapeutic agent with possible prostate cancer clinical applications.