Estimating scatterer properties in rat fibroadenomas using various mathematical form factors

Quantitative ultrasound (QUS) imaging is a model-based approach aimed at lesion detection and classification. In this study, the RF backscattered signals from rat fibroadenomas were fit to various mathematical models to yield effective scatterer diameter (ESD) estimates which are tied to tissue microstructure. The goal of these experiments was to understand potential sources of scattering in live tissue across a wide frequency range and how results from different models compare to one another.