Focused-ultrasound modifications on the conduction properties of toad's sciatic nerve

A histomorphological method has been used universally in the researches on the focused ultrasound modifications on the neural tissues, but the dynamic effect is usually unknown. We report on an electrophysiological method to investigate the time-dependent effect of focused ultrasound on the conduction properties of toad's sciatic nerve. It was noticed that focused ultrasound could make the CAPs descend significantly and rapidly after a short time (26plusmn3s) of radiation. However, before the nerve was totally damaged, the CAPs had some recoverability once focused ultrasound was stopped.