Study on Si-surface modification with chitosan and cell adhesion

Chitoan was immobilized on silicon surface by(3-aminopropyl) triethoxysilane (APTES) ldquobridgerdquo. Contact angle measurement and Auger electron spectroscopy (AES) was used to characterize steps of the process. L929 Cells were used to evaluate the biology effect of the modification. The results have shown that the chitosan modification could depress the adhesion of cells on silicon.