Comparison of two 3D implementations of TOF scatter estimation in 3D PET

Time-of-Flight (TOF) PET requires the development of TOF scatter estimation methods. Two different approaches for modeling TOF 3D scatter are presented in this paper. We performed Monte Carlo simulations to compare the two methods. Both methods resulted in good agreement with Monte Carlo simulations. In addition, the second method is independent of the number of timing bins used and therefore, computationally less intensive.