Chronic Neural Recording with a 64-Channel Cortical Microsystem

This paper presents initial neural recording results with a 64-channel wireless cortical microsystem. The system can be programmed and powered using an inductive telemetry link, switching an RF carrier between 4 and 8MHz to enter command information. Recorded neural activity is returned to the external world wirelessly over an on-off-keyed 80MHz carrier. The system can be programmed to detect positive, negative, and biphasic spikes on all the channels simultaneously or can monitor one channel with 8 bits of resolution. It has recorded single units from guinea pig auditory cortex over periods of 30 days.