Biological mechanisms on-a-chip

In this paper, we present simulation and hardware realization of the growth hormone secretion mechanism. The mechanism is realized on a Xilinx FPGA XSA-50 board. To realize the mechanism, a mathematical model based on bio-mathematical nonlinear delay differential equations has been implemented. The model is then simulated on the computer's screen using hardware description language (HDL). The simulation depicts the antagonistic and stimulatory interaction of growth hormone, growth hormone releasing hormone (GHRH), and somatotropin release-inhibiting factor (SRIF). After verification, the simulation is synthesized and downloaded onto field programmable gate array (FPGA) Xilinx XSA-50 microchip. The microchip sequentially outputs the decimal equivalents of the respective hormones. The chip is tested by comparing its output with that of the simulation. Our results show that the output of the chip and the simulation are identical