Dynamic 'In Vivo' Performance of Temperature Controlled Local Microwave Hyperthermia at 2.45 GHz

A microwave system was constructed, suitable for local heating of animal tumours. The system basically consists of a 2.45 GHz generator, operating in a pulsed power mode, a micro-thermocouple temperature monitoring equipment and different applicators. Performance was tested on phantom tissue and by heating solid rat tumours, revealing differences in the heating response of the control-loop when both cases are compared. The system is capable of heating the tumours to a desired temperature level (eq. 43 °C) and maintains temperature within +- 0.1°C during treatment.