Microwave Imaging for Breast Cancer Screening: Initial Clinical Insights from the MammoScreen Project

Microwave imaging has gained attention for its potential in medical applications, particularly breast cancer imaging. The use of safe, non-ionizing radiofrequency signals makes it a promising alternative for early detection in screening programs. This study presents preliminary findings from a clinical investigation in one of the centers using the microwave imaging MammoWave^® device, enhanced by a machine learning-based clinical decision support system (CDSS). Conducted across nine European hospitals, the clinical study (ClinicalTrials.gov: NCT06291896) aims to validate MammoWave’s sensitivity (>75%) and specificity (>90%) using data from 10,000 volunteers. Initial results from 760 volunteers indicate high compliance and promising lesion detection capabilities, although additional efforts should be made to achieve balanced sensitivity and specificity. As this is a work-in-progress study, ongoing data collection and analysis will be crucial to refining MammoWave’s clinical performance. By sharing these preliminary results, we aim to foster discussion, gather critical feedback, and explore potential refinements in microwave-based imaging.