An Intersection Point Detection Method in Direct Binary-Scale Amniotic Fluid Bag Chromosome Images Using Hit-Or-Miss Transformation for Automatic Chromosome Number Determination

The problem of amniotic chromosome counting errors is caused by chromosomal ambiguity. For example, chromosomal overlap results in misidentification of the overlap point in chromosomal skeleton images. The overlapping points of the chromosomal skeleton images are important features used in counting the amniotic sac chromosomes. Therefore, this research presents a method (Crosspoint Detection in Overlap Chromosomal Structures: A Directional Binary Approach: CDOCS-DBA). This method is developed based on Direct Binary-Scale and Hit-or-Miss Transformation. This method improves the efficiency of identifying overlapping points in amniotic chromosome images. The proposed method can improve the efficiency of amniotic chromosome counting with a yield of 81.48% for ambiguous amniotic chromosomes.