Adoption of Controls and Saga of Development in 3D Printed Bioimplants : A Business Perspective

3D bioprinting is gaining immense importance in the biofabrication of organs, cartilages, bones, tissue repair or regeneration in tissue-engineered applications, personalized medicine, tailored therapies, and pharmaceutical testing. This study envisages the types of controls employed in the production of 3D printed bioimplants, which is either implemented through the use of digital control or action perceived with respect to response to stimuli, using various materials, printing techniques, and enabling technologies of Industry 4.0. Different search strings like ”enabling technologies” and ”controls” are used in the 3D printing of bioimplants, which are confined to computer science for the exploration of scientific literature from the Scopus database. The systematic literature review methodology of the extracted literature gives an insight into critical concepts, present status, publication trends, research domains, a survey of controls implemented in 3D printing of bioimplants since inception, and presents research directions for future work. This article underscores the significance of 3D bioprinting for business managers and practitioners in terms of opportunities and challenges, business model innovation, decision-making, costbenefit analysis, regulatory landscape, ethical and societal considerations, supply chain integration, market adoption barriers, and helping organizations achieve sustainability, precise control, biodegradability, efficiency, reliability, safety, and collaboration