Research On Renova New Domestic Mechanical Detachable Coil System in Experimental Swine Aneurysm

Objective: To establish an animal aneurysm model and use it to verify the operation performance, safety and effectiveness of Renova coil, a new domestic mechanical release coil system.Methods: Six healthy adult Guizhou swines were selected to make lateral aneurysm models on their common carotid artery by microsurgical suture. Renova coils were implanted immediately after angiography confirmation. Observe the operating performance of the coil during implantation. The occlusion of the aneurysm model immediately after the coil implantation and 6 months after embolization were evaluated by angiography. The specimens of the aneurysm model were examined pathologically.Results: The operating performance of coil were excellent. There were no complications such as perforation, displacement and thrombosis of parentartery. The immediate complete occlusion rate (Raymond-Roy Classification I) was 83.33%. The complete occlusion rate of aneurysm model was 100.00% after 6 months embolization. Pathology showed that the intima of the neck of the aneurysm model was completely closed and the lumen of the aneurysm model was tightly packed.Conclusion: Renova, a new domestic mechanical release coil system, has excellent performance in the main operation performance and use safety in the experiment of aneurysm model, and excellent performance in the immediate occlusion rate and 6-month occlusion rate of aneurysm model.