Transcranial Photobiomodulation (tPBM) as Alzheimer's Therapy

Brain photobiomodulation therapy using near infrared light (NIR) is a therapy for a variety of neurological and psychological conditions, especially for dementia and Alzheimer. The aim of this research is to design a brain photobiomodulation therapy device to relieve the symptoms of Alzheimer disease. This therapy device used NI) light emitted by a laser diode with a wavelength of 600 - 1100 nm. The recommended therapeutic dose is 1–20 J. The author makes a timer setting 20 minutes with total energy of 15.906 J. The measurement of the wavelength on the LED obtained an average result of 635.1875 nm with a measurement uncertainty of ±2.74 and the wavelength measurement on the laser diode is obtained results >780 nm with a measurement uncertainty of ±0.50. The voltage measurement was carried out 6 times using a Handheld Oscilloscope measuring instrument. The average measured on the LED is 3.351 Volts with a measurement uncertainty of ±0.00082. The average measured on the laser diode is 1,550 Volts with a measurement uncertainty of ±0.011. Current measurements were performed 6 times using a Handheld Oscilloscope. The average measured on the LED is 3.22 mA with a measurement uncertainty of ±0.01. The average measured on the laser diode is 1.59 mA with a measurement uncertainty of ±0.0004. From the test results it can be stated that the device is in good condition and can work according to its function.