A Compartmentalized Approach to the Assembly of Physical Maps

We propose a novel compartmentalized method for the assembly of physical maps from fingerprinted clones. Our assembler exploits the presence of genetic markers at the global level to improve the accuracy of the assembly. Experimental results on the genome of rice and barley demonstrate that the compartmentalized assembler produces significantly more accurate maps, and that it can detect and isolate clones that induce chimeric contigs.