Implanted Wireless Intramedullary Fluid Modulator for Bone Density Augmentation

Intramedullary fluid flow and pressure modulation has been reported to stimulate bone. However, the lack of engineered and implantable devices has been a stumbling block for exploiting the methodology for treatment of osteoporosis. In this paper, we report a wirelessly operated, battery-less, and implantable intramedullary fluid modulator for in-vivo study of intramedullary flow and pressure modulation. Static pressure and dynamic pressure measurements were carried out to investigate the magnetic excitations and pressure responses. In-vivo study of intramedullary pressure modulation was conducted to confirm the fluid modulator induce on-demand intramedullary pressure up to ~38 mmHg amplitude in wireless operations.