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IEEE Engineering in Medicine and Biology Magazine

Issue 6 • Date Nov/Dec 1995

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Displaying Results 1 - 16 of 16
  • The role of juries in patent cases

    Publication Year: 1995
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (156 KB)

    What should be the role of juries in patent cases? That was the question before the Court of Appeals for the Federal Circuit (CAFC) in two recent cases, Markman vs. Westview Instruments Inc. and Hilton Davis Chemical Co. vs. Warner-Jenkinson Co. As technology has become more complex, questions have been raised as to whether lay juries (or lay judges) are able to understand and make meaningful deci... View full abstract»

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  • Engineering in genomics. Technical improvements in high throughput genome sequencing

    Publication Year: 1995, Page(s):794 - 797
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (428 KB)

    High-throughput DNA sequencing of the C. elegans genome currently is ongoing at our Genome Sequencing Center (GSC) at Washington University School of Medicine in St. Louis and at the Sanger Centre in Hinxton, England. Our collaborative effort is aimed at completion of this 100 Mb genome by the end of 1998. Now just into our fifth year of sequencing, we have amassed a combined output of over 22 Mb ... View full abstract»

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  • Brief guide to information resources supporting the Human Genome Project

    Publication Year: 1995, Page(s):760 - 761
    Cited by:  Patents (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (296 KB)

    The following topics are discussed: Human Genome Project information, including the Human Genome News; lists of genome databases worldwide; lists of genome centers worldwide; lists of molecular biology-oriented WWW servers; example of WWW servers that provide links with multiple databases; molecular biology software collections; short descriptions of example molecular biology databases (abstracted... View full abstract»

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  • Texture analysis of CT images

    Publication Year: 1995, Page(s):781 - 786
    Cited by:  Papers (50)  |  Patents (2)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (600 KB)

    The present study has shown some promise in the use of texture for the extraction of diagnostic information from CT images. A number of features are obtained from abdominal CT scans of the liver using the spatial domain statistical texture analysis methods: SGLDM, GLRLM, and GLDM. This study investigated whether (a) the texture could be used to discriminate among the various tissue types that are ... View full abstract»

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  • Integrated access to heterogeneous data from NCBI

    Publication Year: 1995, Page(s):730 - 736
    Cited by:  Papers (3)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (808 KB)

    The National Center for Biotechnology Information (NCBI) was created by Congress in 1988 to provide a stable government entity with a leadership role in coping with the information issues associated with this field. The NCBI Software Toolkit permits software tools to be developed in a heterogeneous environment. The use of abstract syntax notation (ASN.I) allows one to specify and exchange data acr... View full abstract»

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  • Information infrastructure

    Publication Year: 1995, Page(s):746 - 759
    Cited by:  Papers (2)  |  Patents (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1580 KB)

    The original goals of the Human Genome Project (HGP) were: 1) construction of a high-resolution genetic map of the human genome: 2) production of a variety of physical maps of all human chromosomes and of the DNA of selected model organisms; 3) determination of the complete sequence of human DNA and of the DNA of selected model organisms; 4) development of capabilities for collecting, storing, dis... View full abstract»

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  • An expert system for monitoring psychiatric treatment

    Publication Year: 1995, Page(s):776 - 780
    Cited by:  Papers (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (412 KB)

    A number of medical expert systems have been developed to address problems in health care, but there have been few applications to date for psychiatric practice. We have previously discussed design and implementation issues specific to this medical specialty, and have described OVERSEER, a prototype expert system for monitoring drug treatment in a psychiatric setting. Since its initial implementat... View full abstract»

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  • A new design for the genome sequence data base

    Publication Year: 1995, Page(s):725 - 729
    Cited by:  Papers (1)  |  Patents (4)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (688 KB)

    Five years have passed since the Genome Sequence DataBase (GSDB, but at that time GenBank) implemented a first version of the Electronic Data Publishing (EDP) paradigm. The database operation is again being completely redesigned, with the overall philosophy of continually measuring and improving the services provided. The three major goals of the redesign are to: (1) bring the implementation of ED... View full abstract»

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  • An adaptive smoothing filter for URTURlP images

    Publication Year: 1995, Page(s):762 - 765
    Cited by:  Papers (5)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (452 KB)

    The authors have derived an adaptive smoothing filter from a recent clustering method based on information theory and statistical mechanics developed by Y.F. Wong (see Neural Computation, vol. 5, p. 89-104, 1993). It attenuates the noise by smoothing while preserving the edges, according to the desired level of description and is "specified" by two scale parameters. These two scale parameters are ... View full abstract»

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  • Informatics and the Human Genome Project

    Publication Year: 1995, Page(s):694 - 701
    Cited by:  Papers (7)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1128 KB)

    Information technology is transforming biology, and the relentless effects of Moore's Law are transforming that transformation. Nowhere are these changes more apparent than in the international collaboration known as the Human Genome Project (HGP). The authors consider the relationship of informatics to genomic research. Topics discussed include: the nature of information technology; Moore's Law; ... View full abstract»

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  • Graph database systems

    Publication Year: 1995, Page(s):737 - 745
    Cited by:  Papers (5)  |  Patents (15)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1192 KB)

    We have investigated using graphs as the foundation for database systems by developing a graph-based DBMS. We have demonstrated that: 1. Graph-based representations are useful for representing genome data. 2. A graph data model tailored to the requirements of genome data can be used as the basis of a database management system. 3. A graph database management system is a viable technology for stori... View full abstract»

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  • Dynamical infrared thermography in humans

    Publication Year: 1995, Page(s):766 - 771
    Cited by:  Papers (19)  |  Patents (1)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (708 KB)

    The observations described here show that the dynamic thermographic experiments could be used in physiological investigations of humans. The temperature dynamics of human skin registered by this method are shown to depend mostly on peripheral blood flow dynamics. Therefore, factors that determine this blood flow can thus be investigated. The experiments show that several factors other than the wel... View full abstract»

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  • LabBase: managing lab data in a large-scale genome-mapping project

    Publication Year: 1995, Page(s):702 - 709
    Cited by:  Papers (4)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (932 KB)

    The Whitehead/MIT Center for Genome Research is engaged in several high-throughput genome-mapping projects, including physical mapping of the human genome and genetic-linkage mapping of the mouse genome. The scale and complexity of the laboratory workflows for these projects make a laboratory information system a necessity. For example, the human physical mapping project has performed over 1.2 mil... View full abstract»

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  • General purpose telemetry for analog biomedical signals

    Publication Year: 1995, Page(s):772 - 775
    Cited by:  Patents (3)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (332 KB)

    The results presented show that the telemetry system described is convenient for transferring analog biomedical signals for a wide range of physiological parameters, even with low-cost standard communication media. The system developed is independent of the types and models of the signal-generating medical devices and is able to communicate worldwide over a broad range of communication medias. The... View full abstract»

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  • Data management and analysis for high-throughput DNA sequencing projects

    Publication Year: 1995, Page(s):710 - 717
    Cited by:  Papers (3)  |  Patents (27)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (1648 KB)

    The rapid advances in molecular biology have begun to shift many of the bottlenecks in genome research from the laboratory to the data analysis facility. The pace at which this has occurred creates a situation in which software development always has to catch up with the flow of data. Since such large-scale processes were not anticipated, the analysis infrastructure has not been fully established.... View full abstract»

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  • Building an integrated mouse genome database: a view from the front line

    Publication Year: 1995, Page(s):718 - 724
    Cited by:  Papers (5)
    Request permission for commercial reuse | Click to expandAbstract | PDF file iconPDF (972 KB)

    The mouse is important as a model for human genetic processes and diseases due to the high degree of similarity between the two genomes. Here, the authors review their experiences and attempt to relay some of the lessons learned, technical and otherwise, in their efforts to build the Mouse Genome Database (MGD). The topics discussed include: the Mouse Genome Project; developing the MGD; online dat... View full abstract»

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Aims & Scope

IEEE Engineering in Medicine and Biology Magazine contains articles on current technologies and methods used in biomedical and clinical engineering.

 

This Magazine ceased publication in 2010. The current retitled publication is IEEE Pulse.

Full Aims & Scope