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# IEEE Transactions on Nuclear Science

## Issue 1  Part 1 • Feb. 2012

This issue contains several parts.Go to:  Part 2

## Filter Results

Displaying Results 1 - 21 of 21
• ### [Front cover]

Publication Year: 2012, Page(s): C1
| PDF (60 KB)
• ### IEEE Transactions on Nuclear Science publication information

Publication Year: 2012, Page(s): C2
| PDF (40 KB)
• ### Table of contents

Publication Year: 2012, Page(s):1 - 2
| PDF (78 KB)
• ### Use of Cramer–Rao Lower Bound for Performance Evaluation of Different Monolithic Crystal PET Detector Designs

Publication Year: 2012, Page(s):3 - 12
Cited by:  Papers (15)
| | PDF (1519 KB) | HTML

We have previously reported on continuous miniature crystal element (cMiCE) PET detectors that provide depth of interaction (DOI) positioning capability. A key component of the design is the use of a statistics-based positioning (SBP) method for 3D event positioning. The Cramer-Rao lower bound (CRLB) expresses limits on the estimate variances for a set of deterministic parameters. We examine the C... View full abstract»

• ### A High-Speed Multi-Channel Readout for SSPM Arrays

Publication Year: 2012, Page(s):13 - 18
Cited by:  Papers (8)
| | PDF (2049 KB) | HTML

Solid-state photomultiplier (SSPM) arrays are a new technology that shows great promise to be used in PET detector modules. To reduce the number of channels in a PET scanner, it is attractive to use resistor dividers, which multiplex the number of channels in each module down to four analog output channels. It is also attractive to have SSPMs with large pixels (3×3 or 4×4 mm... View full abstract»

• ### Towards High-Resolution X-Ray Imaging Using a Structured Scintillator

Publication Year: 2012, Page(s):19 - 23
Cited by:  Papers (3)
| | PDF (1732 KB) | HTML

Structured scintillators, by light-guiding secondary emitted visible photons to a pixel in a CCD or CMOS image sensor, improve the lateral resolution of X-ray imaging detectors. In this work we have fabricated pore arrays in a silicon wafer and subsequently filled them with CsI(Tl) by a melting process. The goal was to down-scale the pore geometry for increased resolution. The results show that al... View full abstract»

• ### Novel Point-Like $^{68}{rm Ge}/^{68}{rm Ga}$ Radioactive Source With Spherical Positron Absorber

Publication Year: 2012, Page(s):24 - 29
Cited by:  Papers (1)
| | PDF (747 KB) | HTML

Purpose: In the conventional techniques for determining the calibration factors of positron emission tomography (PET) scanners, cylindrical water and resin phantoms with radioisotope 18F or 68Ge/68Ga are used. In these methods, however, the results depend on attenuation and scatter correction. The purpose of this study is to develop a point-like 68Ge/... View full abstract»

• ### A High-Rate Energy-Resolving Photon-Counting ASIC for Spectral Computed Tomography

Publication Year: 2012, Page(s):30 - 39
Cited by:  Papers (13)
| | PDF (1423 KB) | HTML

We describe a high-rate energy-resolving photon-counting ASIC aimed for spectral computed tomography. The chip has 160 channels and 8 energy bins per channel. It demonstrates a noise level of ENC =214 electrons at 5 pF input load at a power consumption of <; 5 mW/channel. Maximum count rate is 17 Mcps at a peak time of 40 ns, made possible through a new filter reset scheme, and maximum read-out... View full abstract»

• ### Real-Time Imaging System for the OpenPET

Publication Year: 2012, Page(s):40 - 46
Cited by:  Papers (17)
| | PDF (1020 KB) | HTML

The OpenPET and its real-time imaging capability have great potential for real-time tumor tracking in medical procedures such as biopsy and radiation therapy. For the real-time imaging system, we intend to use the one-pass list-mode dynamic row-action maximum likelihood algorithm (DRAMA) and implement it using general-purpose computing on graphics processing units (GPGPU) techniques. However, it i... View full abstract»

• ### Detecting Small Liver Tumors With $^{111}$In-Pentetreotide SPECT—A Collimator Study Based on Monte Carlo Simulations

Publication Year: 2012, Page(s):47 - 53
Cited by:  Papers (7)
| | PDF (1003 KB) | HTML

In 111In-pentetreotide single-photon emission computed tomography (SPECT), the tumor-to-background-uptake ratio is generally high. The noise is, however, also usually on a high level, and in combination with the low spatial resolution of SPECT, this may lead to difficulties in the detection of small tumors. This is especially the case in regions with a relatively high background activit... View full abstract»

• ### X-Ray Fluorescence Imaging With the Medipix2 Single-Photon Counting Detector

Publication Year: 2012, Page(s):54 - 61
Cited by:  Papers (7)
| | PDF (1364 KB) | HTML

Material-resolved X-ray imaging or colour X-ray imaging is of a great interest for many applications ranging from physics, industry to medicine and biology. X-ray fluorescence offers a method for producing such images if the energies and positions of origin of the fluorescent photons can be adequately resolved. View full abstract»

• ### Finding Optimized Conditions of Slit-Slat and Multislit-Slat Collimation for Breast Imaging

Publication Year: 2012, Page(s):62 - 69
Cited by:  Papers (4)
| | PDF (1221 KB) | HTML

In order to develop a breast-imaging system for Single Photon Emission Computed Tomography (SPECT) using slit-slat and multislit-slat collimators, we searched for optimized geometric parameters of the collimators. For this study, we employed two independent metrics to validate each result: 1)Signal to Noise Ratio (SNR) based on the Cramer-Rao lower Bound (CRB) and 2) contrast at the same noise lev... View full abstract»

• ### Demonstration of in-vivo Multi-Probe Tracker Based on a Si/CdTe Semiconductor Compton Camera

Publication Year: 2012, Page(s):70 - 76
Cited by:  Papers (10)
| | PDF (1083 KB) | HTML

By using a prototype Compton camera consisting of silicon (Si) and cadmium telluride (CdTe) semiconductor detectors, originally developed for the ASTRO-H satellite mission, an experiment involving imaging multiple radiopharmaceuticals injected into a living mouse was conducted to study its feasibility for medical imaging. The accumulation of both iodinated (131I) methylnorcholestenol an... View full abstract»

• ### An Experiment-Based Approach for Predicting Positron Emitter Distributions Produced During Therapeutic Ion Irradiation

Publication Year: 2012, Page(s):77 - 87
Cited by:  Papers (10)
| | PDF (1307 KB) | HTML

In-beam positron emission tomography (PET) is a valuable method for a beam-delivery independent dose monitoring in radiation therapy with ion beams. Up to now, its clinical feasibility has been demonstrated for patient irradiation with carbon ions. From radiobiological point of view it is highly desirable to perform tumor irradiation also with other light ions. To extend the application of in-beam... View full abstract»

• ### Evaluation of a New Regularization Prior for 3-D PET Reconstruction Including PSF Modeling

Publication Year: 2012, Page(s):88 - 101
Cited by:  Papers (7)
| | PDF (4248 KB) | HTML

The response of a PET system can be described by its characteristic Point Spread Function (PSF) representing the spatial degradation of a point source due to physical effects and system design. If the PSF is accounted for in the reconstruction algorithm, better image quality and spatial resolution may be achieved. Un- fortunately, a common behaviour of unregularized iterative reconstruction techni... View full abstract»

• ### Automatic Detection of Lung and Liver Lesions in 3-D Positron Emission Tomography Images: A Pilot Study

Publication Year: 2012, Page(s):102 - 112
Cited by:  Papers (4)
| | PDF (758 KB) | HTML

Positron emission tomography (PET) using fluorine-18 deoxyglucose (18F-FDG) has become an increasingly recommended tool in clinical whole-body oncology imaging for the detection, diagnosis, and follow-up of many cancers. One way to improve the diagnostic utility of PET oncology imaging is to assist physicians facing difficult cases of residual or low-contrast lesions. This study aimed at evaluatin... View full abstract»

• ### Realistic and Efficient Modeling of Radiotracer Heterogeneity in Monte Carlo Simulations of PET Images With Tumors

Publication Year: 2012, Page(s):113 - 122
Cited by:  Papers (9)
| | PDF (2046 KB) | HTML

Monte Carlo simulations are extensively used in PET to evaluate the accuracy with which PET images can yield reliable estimates of parameters of interest. For such applications, the simulated images should be as realistic as possible so that conclusions can be extrapolated to clinical PET images. In this work, we describe a method for introducing realistic modeling of radiotracer heterogeneity int... View full abstract»

• ### Evaluation of the Accuracy and Robustness of a Motion Correction Algorithm for PET Using a Novel Phantom Approach

Publication Year: 2012, Page(s):123 - 130
Cited by:  Papers (4)
| | PDF (819 KB) | HTML

We introduce the use of a novel physical phantom to quantify the performance of a motion-correction algorithm. The goal of the study was to assess a PET-PET image registration, the final output of which is a motion-corrected high-count PET image volume, a procedure called Reconstruct, Register and Average (RRA). Methods: A phantom was constructed using 5 ~ 2 mL Ge-68 filled spheres suspended in a ... View full abstract»

• ### 2012 IEEE membership form

Publication Year: 2012, Page(s):131 - 132
| PDF (1368 KB)
• ### IEEE Transactions on Nuclear Science information for authors

Publication Year: 2012, Page(s): C3
| PDF (26 KB)
• ### Affiliate Plan of the IEEE Nuclear and Plasma Sciences Society

Publication Year: 2012, Page(s): C4
| PDF (18 KB)

## Aims & Scope

IEEE Transactions on Nuclear Science focuses on all aspects of the theory and applications of nuclear science and engineering, including instrumentation for the detection and measurement of ionizing radiation; particle accelerators and their controls; nuclear medicine and its application; effects of radiation on materials, components, and systems; reactor instrumentation and controls; and measurement of radiation in space.

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## Meet Our Editors

Editor-in-Chief
Paul Dressendorfer
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