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Pulse, IEEE

Issue 6 • Date Nov.-Dec. 2011

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Displaying Results 1 - 25 of 31
  • [Front cover]

    Publication Year: 2011 , Page(s): C1
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  • Table of contents

    Publication Year: 2011 , Page(s): 1
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  • Staff listing

    Publication Year: 2011 , Page(s): 2
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  • Wireless [From the Editor]

    Publication Year: 2011 , Page(s): 3 - 5
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  • Call for AdCom Nominations

    Publication Year: 2011 , Page(s): 4
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  • Accomplishments of EMBS [President's Message]

    Publication Year: 2011 , Page(s): 6
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  • Benefits of Starting an EMBS Student Club/Chapter in Your University [Student's Corner]

    Publication Year: 2011 , Page(s): 7
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  • Round Two: Doubt [Perspectives on Graduate Life]

    Publication Year: 2011 , Page(s): 8
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  • The Last Summer of Your Life [Perspectives on Graduate Life]

    Publication Year: 2011 , Page(s): 10
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  • ISBI 2012

    Publication Year: 2011 , Page(s): 11
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  • Delving into BioMEMS [Guest Editorial]

    Publication Year: 2011 , Page(s): 12
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  • IEEE EMBC 2012

    Publication Year: 2011 , Page(s): 13
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  • The Right Tool for the Job

    Publication Year: 2011 , Page(s): 14 - 18
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (1512 KB) |  | HTML iconHTML  

    In the biological world, where the typical human cell is less than 10 μm in diameter, an average bacterium a few micrometers long, and the garden-variety virus about 100 nm in length, more and more researchers view microscopic tools known as biological microelectromechanical systems (bioMEMS) as the right choice for keeping patients alive and healthy. BioMEMS are an outgrowth of MEMS-the sensors, actuators, and other microchips-developed for the electronics industry. MEMS are present in everything from computers and ink-jet printers to automobile air bags and digital video projection systems. View full abstract»

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  • On a Chip

    Publication Year: 2011 , Page(s): 19 - 27
    Cited by:  Papers (1)
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    Biological or biomedical microelectromechanical systems (BioMEMS) are poised to have a significant impact on clinical and biomedical applications. These devices-also termed lab-on-chip or point-of-care (POC) sensors-rep- resent a significant opportunity in various patient-centric settings, including at home, at the doctor's office, in ambulances on the way to the hospital, in emergency rooms (ERs), at the hospital bedside, in rural and global health settings, and in clinical or commercial diagnostic laboratories. The potential impact of these technologies on the early diagnosis and management of disease can be very high for sensing and reporting on parameters ranging from physiological to biomolecular. As health-care delivery and management be- come increasingly personalized and individualized and as genomic, proteomic, and metabolic technologies unravel the human genetic and epigenetic dispositions to disease, detection of multiple markers (at any of the Omics scale) at an individualized level to assess the state of health and disease will become even more important. View full abstract»

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  • Engineering Tissue with BioMEMS

    Publication Year: 2011 , Page(s): 28 - 34
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    The emergence of biological microelectromechanical systems (BioMEMS) technology has been spurred by the development of precise microscale fabrication techniques across a wide range of biomaterials substrates. BioMEMS devices are now finding application in areas ranging from genomics and proteomics to clinical diagnostics and implantable drug delivery systems. The design principles of early lab-on-a-chip devices for point-of-care diagnostics are now being extended to platforms for tissue engineering. View full abstract»

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  • Beyond Proof of Concept

    Publication Year: 2011 , Page(s): 35 - 39
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    Here, two academic bioengineers who have taken this commercialization step will share their experiences and thoughts. First, we discuss this topic with Steve Quake at Stanford University. Prof. Quake has pioneered the development of multilayer microvalves as a way to control complex fluid handling at a microscale. He has spun off the technology into Fluidigm, a company cofounded by him. Fluidigm has sold many of these microfluidic chips for the research biology market. Next, we talk with Shu Takayama from the University of Michigan. Prof. Takayama has developed microfluidic methods for reproductive medicine (Figure 2), which are being commercialized by Incept BioSystems, a company he cofounded. A key requirement of a medical device for use in U.S. clinics is to conduct trials for regulatory approval from the Food and Drug Administration (FDA). The company completed its first human trials in 2010. View full abstract»

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  • Perspective on Diagnostics for Global Health

    Publication Year: 2011 , Page(s): 40 - 50
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    Diagnostic applications for global health have exploded in the past ten years. Numerous articles have been generated on global health priorities, constraints of resource-limited settings, and technological innovations for diagnostics development, including several comprehensive reviews [1]-[3]. In this article, we aim to provide 1) a focused summary of the most highly needed diagnostics, 2) a discussion of noteworthy recent developments of technologies in the field, and 3) a perspective on the evolution, challenges, and future directions of diagnostics for global health applications. View full abstract»

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  • Solving Medical Problems with BioMEMS

    Publication Year: 2011 , Page(s): 51 - 59
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    A routine laboratory exercise for an undergraduate electrical engineering student is to build a simple electronic filter circuit and determine its frequency and transient response. During the exercise, the student exposes the circuit to a range of electrical signals and captures the voltage and current characteristics. The relationship between what the circuit is exposed to and how it responds allows for developing a transfer function that provides insight into how the circuit operates. View full abstract»

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  • Medical Image Analysis

    Publication Year: 2011 , Page(s): 60 - 70
    Cited by:  Papers (3)
    Save to Project icon | Request Permissions | Click to expandQuick Abstract | PDF file iconPDF (4042 KB) |  | HTML iconHTML  

    Since the discovery of the X-ray radiation by Wilhelm Conrad Roentgen in 1895, the field of medical imaging has developed into a huge scientific discipline. The analysis of patient data acquired by current image modalities, such as computerized tomography (CT), magnetic resonance tomography (MRT), positron emission tomography (PET), or ultrasound (US), offers previously unattained opportunities for diagnosis, therapy planning, and therapy assessment. Medical image processing is essential to leverage this increasing amount of data and to explore and present the contained information in a way suitable for the specific medical task. In this tutorial, we will approach the analysis and visualization of medical image data in an explorative manner. In particular, we will visually construct the image processing algorithms using the popular graphical data-flow builder MeVisLab, which is available as a free download for noncommercial research. We felt that it could be more interesting for the reader to see and explore examples of medical image processing that go beyond simple image enhancements. The part of exploration, to inspect medical image data and experiment with image-processing pipelines, requires software that encourages this kind of visual exploration. View full abstract»

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  • Laplace's Law [Retrospectroscope]

    Publication Year: 2011 , Page(s): 71 - 76
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    In the two preceding notes about Laplace's law [1], [2], we first recalled what it is and how it is frequently mentioned or applied in physiology, finding that in this particular case, there is an apparent separation between physiology and physics supposedly backing up the subject. Moreover, mistakes are almost a rule while amazingly and fortunately, the overall practical conclusions after very heavy simplifications are correct and well demonstrated by actual experiments and postmortem studies. The second note dealt with the mathematics of the law, and we believe that we practically exhausted all the pathways leading to the final formula, both when the wall thickness is negligible and when it is finite and significant. Now, our hat displays the epistemologist's sign, up- setting perhaps some readers, but with- out totally leaving out the quantitative view. Hence, the objectives of the note are established as follows: T general objective: To introduce, discuss, and eventually produce answers for the epistemological aspects associated with Laplace's law specific objective: To discern if a mathematical equation has the same reach when obtained from two different physical settings (in our case, a phenomenon found in capillaries and the behavior of hollow stretch- able cavities). View full abstract»

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  • BHI 2012: IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI 2012) - Call for papers

    Publication Year: 2011 , Page(s): 77
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  • Oh Mama, Where's My Comma? [State of the Art]

    Publication Year: 2011 , Page(s): 78
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  • MNMC 2012

    Publication Year: 2011 , Page(s): 79
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  • Scenes from EMBC 2011 Boston

    Publication Year: 2011 , Page(s): 80
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  • EMBS Constitution and Bylaws Changes

    Publication Year: 2011 , Page(s): 83
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Aims & Scope

IEEE Pulse covers both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence

Full Aims & Scope

Meet Our Editors

Editor-in-Chief

Colin J.H. Brenan
HiFiBiO BV
Marblehead, Massachusetts,
United States
E-mail: colin.j.brenan@ieee.org